Abruptly stopping the use of medicines to treat these conditions can have serious consequences. Women should not change medications or stop taking medications without first talking with their doctor about available options. These results reflect not only the new data, but also incorporate results from previously published independent studies.
Researchers found some birth defects occur about two or three times more frequently among babies born to women who took certain SSRI medications, like fluoxetine and paroxetine, early in pregnancy. Through Treating for Two, CDC is working with its partners, other federal agencies, and the public to understand trends in medication use among pregnant women and women of reproductive age, and to provide women and healthcare providers with information about the safety or risk of using specific medications during pregnancy.
This information will allow women and their doctors to make informed decisions about treating health conditions during pregnancy. For more information, visit www. Products and services. Antidepressants: Safe during pregnancy? By Mayo Clinic Staff. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Please try again. Something went wrong on our side, please try again.
Show references Grigoriadis S. Unipolar major depression in pregnant women: General principles of treatment. Accessed Sept. Stewart D, et al. Antenatal use of antidepressants and risk of teratogenicity and adverse pregnancy outcomes: Selective serotonin reuptake inhibitors SSRIs.
Briggs GG, et al. Wolters Kluwer; Mezzacappa A, et al. Risk for autism spectrum disorders according to period of prenatal antidepressant exposure. JAMA Pediatrics. American College of Obstetricians and Gynecologists. Practice Bulletin No. Reaffirmed Antenatal use of antidepressants and risks of teratogenicity and adverse pregnancy outcomes: Drugs other than selective serotonin reuptake inhibitors.
One study found that the risk of miscarriage was similar between women exposed to SSRIs during early pregnancy and women who discontinued SSRI treatment before pregnancy. Although it is safest not to take any antidepressant medication while pregnant, Dr. Lagoy says it may be worse for both mother and baby to discontinue medications like Zoloft during pregnancy since this could potentially lead to worsening mood and anxiety symptoms.
They will be able to advise you on the safest options for your pregnancy. According to Dr. Ross, a safe and recommended dose of Zoloft begins at 25 mg to 50 mg per day. For moderate to severe depression, Dr. Ross says doses up to mg are deemed safe to use during pregnancy.
When managing antidepressants during pregnancy, Dr. Lagoy says he strives to give the minimum dose possible. Lagoy explains. The good news is it is generally considered safe to take Zoloft while breastfeeding. About 30 percent of babies whose mothers take SSRIs will experience neonatal adaptation syndrome, which can cause increased jitteriness, irritability and respiratory distress difficulty breathing , among other symptoms.
If you have a mood disorder, you may benefit from speaking with a reproductive psychiatrist when you are pregnant or thinking about becoming pregnant. Meeting with a doctor after you become pregnant is not too late. Osborne says her approach with patients is to limit the number of potentially harmful exposures to the baby. This means considering the number of medications a mother is on, as well as her psychiatric illness. If your illness is mild, your doctor might recommend getting off medication and replacing it with treatments such as psychotherapy, prenatal yoga or acupuncture to improve your mood.
Ultimately, Osborne says women should weigh the risks of medication against the risk of untreated illness.
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